Scientific Programme

The biennial meeting NeuroGASTRO 2023 is a well-established European event. ESNM is proud to bring together leading experts and emerging young investigators actively involved in neurogastroenterology, digestive motility and functional gastrointestinal diseases from Europe and from all around the world to discuss cutting-edge research. The congress presents the latest in science and education in various formats to suit the needs of all participants, including challenging state-of-the-art lectures.

Main topics of NeuroGASTRO 2023:

  • Mechanisms underlying normal and disordered gastrointestinal function
  • Pain mechanisms and visceral hypersensitivity
  • Role of the microbiome and diet in health and disease, including the role of host-microbe interactions
  • Dietary interventions, including pre-, pro- and syn- and postbiotics
  • Mechanisms and diagnostic techniques in food intolerance
  • Pathophysiological and clinical aspects of disorders of gut-brain interaction
  • Technologies for the assessment of gastrointestinal motility and perception
  • Current and future therapies for disordered gut function and disorders of gut-brain interaction
  • Brain-gut interactions in health and disease
  • Epidemiology of disordered gut function and disorders of gut-brain interaction

Download Programme

All information at a glance: here you can download the programme of NeuroGASTRO 2023 and all organisational details about the meeting.

Abstracts

All abstracts of NeuroGASTRO 2023 have been published in a special issue from Whiley.

AUGUST 31th

Thursday
Crown Ballroom: 14.00 - 19.30
Magnolia Room: 08.30 - 17.28
Primavera Room: 16.00 - 17.29

Crown Ballroom

13.15 - 14.00 Poster Session (Orhideea room)

14.00 - 15.30 PLENARY 1 - Opening Ceremony
(Chairs: Qasim Aziz, Daniel Pohl, Magnus Simren, Vasile Drug)
14.00 Welcome address (Qasim Aziz, Daniel Pohl, Magnus Simren, Vasile Drug)
14.30 Endophenotypes in visceral pain: Mechanistic importance for clinical practice? (Qasim Aziz)
14.52 NGS18138-93 - Gut Amyloid-ß Impairs Enteric Nervous System and Causes Gastro-intestinal Dysfunctions in Alzheimer’s Disease Model (Rodrigue Brossaud)
15.07 Lifetime achievement award - Laudatum (Daniel Pohl)
15.17 Lifetime achievement awardee talk (Paul Enck)

15.30 - 16.00 Coffee Break and Poster viewing

16.00 - 17.30 SYMPOSIUM 1 - Eosinophils and mast cells in gastrointestinal disorders
(Chairs: Nathalie Vergnolle, Teodora Surdea-Blaga)
16.00 The role of mast cells in disorders of gut-brain interaction (DGBI)
(Javier Aguilera-Lizarraga)
16.22 Eosinophilic gastrointestinal disorders in 2023: An update
(Edoardo Savarino)
16.44 Functional Dyspepsia: a new eosinophilic gastrointestinal disorder?
(Lucas Wauters)
17.06 Novel drugs targeting eosinophils and mast cells to treat GI symptoms. Hope for the future? (Nicola De Bortoli)
18.15 - 19.30 Welcome Reception
18.00 Welcome Reception (Qasim Aziz, Vasile Drug)
18.05 Romanian Medical Doctor Chamber Orchestra "Dr Ermil Nechifor" - Mini-Concert
18.25 Welcome Reception (Hotel Restaurant)

Magnolia Room

08.30 - 10.00 POSTGRADUATE COURSE - SESSION 1 – Advances in Clinical Measurement and Management of GI Motility & Function
(Chairs: Asma Fikree, Chloé Melchior)
08.30 Oropharyngeal symptoms (Ayodele Sasegbon)
09.00 Eosinophilic oesophagitis (Danila Guagnozzi)
09.30 Rumination (Daniel Sifrim)
10.00 Belching (Daniel Sifrim)

10.30 - 11.00 Coffee Break

11.00 - 12.30 POSTGRADUATE COURSE - SESSION 2 Advances in Clinical Measurement and Management of GI Motility & Function
(Chairs: Asma Fikree, Chloé Melchior)
11.00 Avoidant/restrictive food intake disorder (ARFID) (Chloé Melchior)
11.30 Chronic Intestinal Pseudoobstruction (CIPO) (Carolina Malagelada)
12.00 Anorectal pain (Giuseppe Chiarioni)
12.45 - 13.00 INDUSTRY HIGHLIGHTS

Restoring intestinal comfort in patients with irritable bowel syndrome (Lucian Negreanu)

13.15 - 14.00 Poster Session (Orhideea room)

16.00 - 17.28 SYMPOSIUM 2 - THE ROLE OF THE MICROBIOME IN BRAIN AND MOOD DISEASES
(Chairs: Gerard Clarke, Paul Enck)
16.00 Microbiome in anxiety and depression (Mireia Valles-Colomer)
16.22 Gut Microbiota and Neuroinflammatory Response after Stroke: Role of Barrier Function (Vikramjeet Singh)
16.44 NGS18210-84 - Modelling Psychiatric Comorbidity in Irritable Bowel Syndrome: Focus on the Role of the Microbiome-Gut-Brain Axis in Stress and Resilience (Lard Wilmes)
16.59 NGS18145-91 - Extracellular vesicles: mediators of communication between the gut microbiota and enteric neurons in autism spectrum disorders (Caillaud Martial)
17.14 NGS18313-88 - Fecal microbiota from adult with autism spectrum disorder alters brain and digestive functions in recipient mice (Morgane Eileen Le Dréan)

Primavera Room

16.00 - 17.29 SYMPOSIUM 3 - SYSTEMIC DISEASES AND GI DYSMOTILITY
(Chairs: Jutta Keller, Niall Hyland)
16.00 GI dysfunction in inflammatory connective tissue disorders (Roberto De Giorgio)
16.22 GI manifestations of diabetes mellitus (Asbjørn Mohr Drewes)
16.44 NGS18161-89 - Pooled Efficacy
Analysis of Tradipitant in Idiopathic and Diabetic Gastroparesis Study VP-VLY-686-3301 and VP-VLY-686-2301 (Jesse Carlin)
16.59 NGS18147-93 - Small bowel dysmotility on manometric evaluation is an independent predictor of mortality (Heithem Soliman)
17.14 NGS18226-91 - Regulation of 5-HT secretion from human duodenal enterochromaffin cells (Constanza Alcaino)

SEPTEMBER 01st

Friday
Crown Ballroom: 07.30 - 18.30
Magnolia Room: 11.00 - 17.30
Primavera Room: 11.00 - 17.30

Crown Ballroom

07.30 - 09.00 THE ROMANIAN SOCIETY OF NEUROGASTROENTEROLOGY SESSION: HOW TO BUILD A NEUROGASTROENTEROLOGY UNIT
(Chairs: Mircea Diculescu, Radu Tutuian)
07.30 Why is it necessary to have a dedicated Neurogastroenterology Unit? (Vasile Drug, Oana Barboi)
07.52 How to set up a Neurogastroenterology Unit: Equipment, staffing, training
(Radu Tutuian)
08.14 Integrating a Neurogastroenterology Unit in the Department / Hospital / Referring network (Dan Dumitrascu, Teodora Surdea-Blaga)
08.36 Quality Control of the Neurogastroenterology Unit (Ion Bancila, Anca Dimitriu)
09.00 - 10.30 PLENARY SESSION 2 – HIGHLIGHTS
(Chairs: Daniel Pohl, Gerard Clarke)
09.00 The stressed gut and the microbiome (Niall Hyland)
09.22 What is the relevance of circadian clocks in the digestive system (Inge Deporteere)
09.44 NGS18194-95 - Disorders of gut-brain interaction in patients with Hypermobile Ehlers-Danlos Syndrome/Hypermobility Spectrum Disorders:
Characterisation of co-morbidities and quality of life (Anisa Choudhary)
09.59 NGS18187-97 -Kronos: Circadian Rhythmicity Analysis in Microbiome and other ‘omics Datasets (Thomaz FS Bastiaanssen)
10.14 NGS18077-95 - Association of Moderate-Intensity and Vigorous-Intensity Physical Activity on Gastroesophageal Reflux Disease (Chung Hyun Tae)

10.30 - 11.00 Coffee Break and Poster viewing

11.00 - 12.30 SYMPOSIUM 4 - FECAL MICROBIOTA TRANSPLANTATION (FMT): STATE OF THE ART IN 2023
(Chairs: Christina Brock, Kristin Elfers)
11.00 FMT in Europe: Current indications (Juozas Kupcinskas)
11.22 FMT in the future: a look in the crystal ball (William Fusco)
11.44 FMT for disorders of gut-brain interaction: Current evidence and how to progress? (Peter Holger Johnsen)
12.06 Effects on gut microbiota composition and function of FMT (Jeroen Raes)

12.30 - 14.00 Lunch Break

12.45 - 13.20 INDUSTRY LUNCH SYMPOSIUM

Advanced therapies for the treatment of refractory nausea and vomiting (Anton Emmanuel) 

13.15 - 14.00 Posters (Orhideea Room)

14.00 - 15.30 SYMPOSIUM 7 - GASTROESOPHAGEAL REFLUX DISEASE IN 2023
(Chairs: Edoardo Savarino, Amir Mari)
14.00 The spectrum of reflux syndrome in clinical practice (Radu Tutuian)
14.22 GERD, Functional Dyspepsia and IBS: overlapping entities requiring a multistep approach (Serhat Bor)
14.44 Diagnosis of GERD: Is it time to revise the Lyon Consensus? (Paola Iovino)
15.06 Endoscopic and surgical approach for GERD: Updates from the most recent guidelines (Matteo Ghisa)

15.30 - 16.00 Coffee Break and Poster viewing

16.00 - 17.30 SYMPOSIUM 10 - BIO-ELECTRICAL NEUROMODULATION FOR GI DISORDERS
(Chairs: Jutta Keller, Hans Törnblom)
16.00 Effectiveness and mechanisms for bioelectrical neuromodulation (Christina Brock)
16.22 Vagal nerve stimulation: how does it work and when is it indicated now and in the future? (Ahmed Albusoda)
16.44 Gastroparesis: Can it be treated with electrical stimulation? (Guillaume Gourcerol)
17.06 Sacral nerve stimulation for colorectal diseases: Where are we and where are we heading? (Ugo Grossi)
17.30 - 19.15 The best of the Little Brain Big Brain (LBBB) meeting
(Chairs: Peter Neckel, Constanza Alcaino)
17.30 Ingestible devices for neuromodulation (Khalil Ramadi)
17.45 Contributions of extrinsic neural pathways to pain and dysmotility during colon inflammation (Kristen Smith-Edwards)
18.00 Glutamatergic circuitry regulates intestinal motility (Ryan Hamnett)
18.15 Characterising the role of human CCK-secreting I-cells in nutrient sensing (Marta Santos Hernandez)

Magnolia Room

11.00 - 12.30 SYMPOSIUM 5 - PSYCHOLOGICAL FACTORS IN DISORDERS OF GUT-BRAIN INTERACTION (DGBI)
(Chairs: Gerard Clarke, Dan Dumitrascu)
11.00 Psychological Comorbidity in Irritable Bowel Syndrome (Javier Santos)
11.22 The Enduring Effects of Stress on the Microbiota gut-brain Axis (Gerard Clarke)
11.44 Neuromodulators in the Treatment of DGBI (Hans Törnblom)
12.06 Behavioural therapies for DGBI (Dipesh Vasant)

12.30 - 14.00 Lunch Break

13.15 - 14.00 Posters (Orhideea Room)

14.00 - 15.30 SYMPOSIUM 8 - P0ST-INFLAMMATORY ABDOMINAL PAIN: PATHWAYS FROM IBD TO IBS
(Chairs: Qasim Aziz, Vasile Drug)
14.00 Neural mechanisms of post inflammatory abdominal
pain – translation from bench to bedside (David Bulmer)
14.22 Neuroimmune and epithelial factors that mediate post-inflammatory chronic pain: are therapeutic targets a reality (Nathalie Vergnolle)
14.44 Role of gut microbiota in modulating the gutbrain
axis in chronic post-inflammatory pain: is there a therapeutic role for probiotics? (Frederic Carvalho)
15.06 Psychosocial factors in post-inflammatory pain – when IBD becomes IBS! (Sigrid Elsenbruch)

15.30 - 16.00 Coffee Break and Poster viewing

16.00 - 17.30 SYMPOSIUM 11 - ESOPHAGEAL MOTILITY DISORDERS AFTER CHICAGO CLASSIFICATION V4.0
(Chairs: Edoardo Savarino, Danila Guagnozzi)
16.00 Classification of esophageal motility disorders: advantages and pitfalls (Jordi Serra)
16.22 Assessment of esophageal symptoms: is high resolution manometry enough? (Frank Zerbib)
16.44 A subset of patient categories that
Chicago classification ver. 4.0 did not describe:
Patients with nonspecific findings in high-resolution
manometry who have dysphagia due to poor distensibility of the thickened esophageal wall (Jin Young Choi)
17.06 Additional diagnostic yield of rapid drink challenge in Chicago Classification version 4.0 compared with 3.0 (Hoyoung Wang)
17.28 Not only a Reflux-related disorder: Pathologies Associated with Hiatus Hernia Based on Big Data Analysis (Amir Mari)

Primavera Room

11.00 - 12.30 SYMPOSIUM 6 - THE ROLE OF THE ENTERIC IMMUNE SYSTEM IN GASTROINTESTINAL HEALTH AND DISEASE
(Chairs: Adrian Goldis, Daisy Jonkers)
11.00 Local immune responses and modulation of the
ENS: Lessons from animal models (Monica Sanchez-Ruiz)
11.22 Neuroimmune mechanisms in disorders of gut-braininteractions (Guy Boeckxstaens)
11.44 NGS18023-86 - Mechanosensitive enteric neurons in the guinea pig stomach - Sophia Mayr
11.59 NGS18154-91 - TRPV4-mediated colonic afferent activation is driven by mucosal ATP and glutamate (Michelle Meng)
12.14 NGS18131-86 - To die or not to die: that is a Dickkopf question (Melanie Scharr)

12.30 - 14.00 Lunch Break

13.15 - 14.00 Posters (Orhideea Room)

14.00 - 15.30 SYMPOSIUM 9 - BARRIER FUNCTION IN NEUROGASTROENTEROLOGY
(Chairs: Javier Santos, Giovanni Barbara)
14.00 Role of Intestinal Permeability in Gastrointestinal Disorders (Ricard Farré)
14.22 Modulation of Intestinal Epithelial Permeability: Lessons Learned from Cell Culture Models (Daisy Jonkers)
14.44 NGS18249-96 - The effect of corticotropin-releasing hormone on duodenal permeability and immune activation in healthy volunteers (Jolien Schol)
14.59 NGS18200-83 - Epithelial and vascular barriers are compromised in Irritable Bowel Syndrome: implications for intestinal and extra-intestinal symptom development (Giovanni Barbara)
15.14 NGS18289-00 - Intestinal permeability in irritable bowel syndrome (IBS) and IBS comorbid: results from DISCOvERIE project (Alice Rustichelli)

15.30 - 16.00 Coffee Break and Poster viewing

16.00 - 17.30 SYMPOSIUM 12 - DIET AND MICROBIOME IN HEALTH AND DISEASE
(Chairs: Daniel Keszthelyi, Magnus Simren)
16.00 Restrictive diets for DGBI: lights and shadows (Sanna Nybacka)
16.22 The link between diet, microbiome and metabolism (Mireia Valles-Colomer)
16.44 NGS18190-91 - Interobserver agreement rate of confocal laser endomicroscopy images in irritable bowel syndrome (Lukas Michaja Balsiger)
16.59 NGS18248-95 - Patients with hypermobile Ehlers Danlos Syndrome (hEDS) fall into four clinically distinct diet phenotypes - a dietary pattern analysis (Rabia Topan)
17.14 NGS18300-84 - Pain-reduction Effect of a Rationally-Designed Live Bacterial Consortium for Treatment of IBS Based on Microbiome Functional Genomics Analysis (Yehuda Ringel)

SEPTEMBER 02nd

Saturday
Crown Ballroom: 08.80 - 16.30
Magnolia Room: 08.00 - 15.30
Primavera Room: 09.00 - 15.40

Crown Ballroom

08.00 - 9.00 Tandem Session
(Chairs: Chloé Melchior, Kristin Elfers)
  Project presentation of the winning TANDEM team of the TANDEM meeting on August 29 - 30, 2023 and introduction of the neuroGASTRO TANDEM meeting itself.
09.00 - 10.30 SYMPOSIUM 13 - ROME FOUNDATION SYMPOSIUM: PROGRESS IN GASTRODUODENAL DISORDERS OF GUT-BRAIN INTERACTION
(Chairs: Jan Tack, Magnus Simren)
09.00 Epidemiology of gastroduodenal disorders (in Europe) (Ami Sperber)
09.22 Management of dyspepsia – West versus East Europe (Agata Mulak)
09.44 Dyspepsia versus gastroparesis: current and emerging views (Jutta Keller)
10.06 Cyclic vomiting syndrome and cannabinoid hyperemesis syndrome:
similarities and distinctions (Maura Corsetti)

10.00 - 15.00 HANDS-ON COURSE FOR GASTROINTESTINAL MANOMETRY AND FUNCTIONAL INVESTIGATIONS*
(Coordinator: Radu Tutuian, Local Coordinator: Cristian Gheorghe) Serhat Bor, Ahmed Albusoda, Ion Bancila, Anca Dimitriu, Teodora Surdea-Blaga, Liliana David

VENUE: CLINICAL INSTITUTE FUNDENI
Digestive Endoscopy Department Șoseaua Fundeni 258, 022328 Bucharest
* In presence only

10.30 - 11.00 Coffee Break and Poster viewing

11.00 - 12.30 SYMPOSIUM 16 - FUNCTIONAL IMPLICATIONS OF ENDOSCOPIC INTERVENTIONS - NEUROGASTROENTEROLOGY AND DIGESTIVE ENDOSCOPY (Joint ESGE-ESNM Symposium)
(Chairs: Daniel Pohl, Jan Martinek)
11.00 POEM – Achalasia (Marcel Tantau, Daniel Pohl)
11.30 C-POEM - Zenker/Spastic UES (Jan Martinek, Silvia Carrion)
12.00 G-POEM – Pylorus /Gastroparesis (Jan Martinek, Daniel Pohl)

12.30 - 14.00 Lunch Break

12.45 - 13.20 INDUSTRY LUNCH SYMPOSIUM

The use of Endoflip in the evaluation of dysphagic and dyspeptic symptoms (Jan Martinek, Daniel Pohl)

13.15 - 14.00 Posters (Orhideea Room)

14.00 - 15.30 SYMPOSIUM 19 - MAST CELL ACTIVATION SYNDROME, JOINT HYPERMOBILITY, PoTS AND HEREDITARY ALPHATRYPTASEMIA: IMPORTANT CAUSES OF GI SYMPTOMS?
(Chairs: Goran Hauser, Jean Marc Sabaté)
14.00 The complexity of mast cell activation syndrome and its role in gastrointestinal disorders (Javier Santos)
14.22 Hereditary alpha-tryptasemia and implications for gastrointestinal disorders (Paula Galvan)
14.44 Joint hypermobility and gastrointestinal dysfunction (Asma Fikree)
15.06 Postural tachycardia syndrome (PoTS) and gastrointestinal symptoms: Is there a link? (Imran Aziz)
15.40 - 16.30 CLOSING CEREMONY & AWARD WINNINGS
(Chairs: Qasim Aziz, Magnus Simren, Giovanni Barbara, Vasile Drug)
15.40 Closing Ceremony & Abstract Awards

Magnolia Room

08.00 - 9.00 Late Breaking Abstract Submission
(Chairs: Nicolas Cenac, Roberto De Giorgio)
08.00 Promotion of physical activity with a mobile app is superior to prescription alone in improving symptoms in patients with irritable bowel syndrome: a randomized controlled trial (Andrea Costantino)
08.10 Mechanisms underlying nutrient sensing in human glucose-dependent insulinotropic peptide secreting K cells (Nunzio Guccio)
08.20 NGS18735-96 - Tradipitant effective in the reduction of vomiting associated with motion sickness across varied sea conditions (Vasilios M. Polymeropoulos)
08.30 Transcriptomic profiling reveals a pro-nociceptive role for Angiotensin II in inflammatory bowel disease (David Bulmer)
08.40 NGS18734-95 - Double-blinded confocal laser endomicroscopy followed by food elimination and reintroduction in patients with irritable bowel syndrome (IBS) (Amanda Blomsten)
09.00 - 10.30 SYMPOSIUM 14 - UPDATE ON THE CLINICAL MANAGEMENT OF FECAL INCONTINENCE
(Chairs: Ugo Grossi, Dan Dumitrascu)
09.00 Etiology, pathogenesis and pathophysiology (Daniel Keszthelyi)
09.22 Diagnostic approach (Mark Fox)
09.44 Medical and behavioral therapy (Giuseppe Chiarioni)
10.06 Surgical treatment options (Emma Carrington)

10.30 - 11.00 Coffee Break and Poster viewing

11.00 - 12.30 SYMPOSIUM 17 - AGEING AND GI FUNCTION AND DYSFUNCTION
(Chairs: Gabriel Prada, Jutta Keller)
11.00 Normal GI physiology: The effect of ageing (Gareth Sanger)
11.22 Disorders of gut-brain interaction and ageing: lessons learnt from the Rome Foundation Global Epidemiology Study (Ami Sperber)
11.44 Swallowing disorders and ageing (Pierfrancesco Visaggi)
12.06 Anorectal disorders and ageing (Emma Carrington)

12.30 - 14.00 Lunch Break

13.15 - 14.00 Posters (Orhideea Room)

14.00 - 15.30 SYMPOSIUM 20 - CURRENT AND FUTURE MANAGEMENT OF CONSTIPATION (Chairs: Luis Novais, Maura Corsetti)
14.00 Constipation: Diagnostic approach in 2023 (Ugo Grossi)
14.22 Current and future drugs for constipation (Jan Tack)
14.44 NGS18239-95 -Naloxegol restores codeine-induced inhibition of high-amplitude propagating contractions and increase of retrograde contractions in a randomized, three-way crossover colonic highresolution
manometry study in healthy volunteers (Annelies Verheyden)
14.59 NGS18116-89 - An artificial intelligence model for time series classification: prediction of delayed balloon expulsion test using high-resolution anorectal manometry data and time-series integrated pressurized volume (Myeongsook Seo)
15.14 NGS18141-87 - Impact of the demy-elination on the enteric nervous system in a murine model of multiple sclerosis (Sofia Faggin)

Primavera Room

09.00 - 10.30 SYMPOSIUM 15 - MECHANISMS OF ABDOMINAL PAIN FROM BENCH TO BEDSIDE
(Chairs: René van den Wijngaard, Sigrid Elsenbruch)
09.00 Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system (Benedicte De Winter) (pre-recorded)
09.22 Role of Bacterial and Host Lipids in visceral Hypersensitivity (Nicolas Cenac)
09.44 Genetic factors of importance for visceral pain (Mauro D‘Amato)
10.06 Is there a role for brain imaging in defining biomarkers of visceral pain in disorders of gut-brain interaction? (Lukas Van Oudenhove)

10.30 - 11.00 Coffee Break

11.00 - 12.30 SYMPOSIUM 18 - NEUROGASTROENTEROLOGY 3.0 / NEUROGASTROENTEROLOGY IN A VIRTUAL WORLD
Chairs: Asbjørn Mohr Drewes, Kristin Elfers)
11.00 How to increase your social Network in neurogastroenterology? (Chloé Melchior)
11.22 Where to find digital training of excellence in neurogastroenterology? (Edoardo Savarino)
11.44 How to increase the impact of your work: Advise from the Editor (Maura Corsetti)
12.06 Mobile apps, digital education, and development of online research platforms (Daniel Keszthelyi)

12.30 - 14.00 Lunch Break

13.15 - 14.00 Posters (Orhideea Room)

14.00 - 15.40 SYMPOSIUM 21 - COVID AND NEUROGASTROENTEROLOGY
(Chairs: Ram Dickman, Mihaela Fadgyas-Stanculete)
14.00 Prevalence of Gastrointestinal Symptoms in Severe Acute Respiratory Syndrome Coronavirus 2 Infection (Giovanni Barbara)
14.22 Neuroimmunology and the psychological symptoms of long-COVID (Mihaela Fadgyas-Stanculete)
14.44 NGS18265-94 - Prevalence and risk factors for post COVID-19 functional gastrointestinal disorders after one year (Maryam Soheilipour)
14.59 NGS18209-92 - Gastroenterologists‘ willingness to work during the COVID-19 pandemic: a comparison in a Romanian sample (Tudor-Stefan Rotaru)
15.14 NGS18306-90 - Gastrointestinal symptoms of SARS-COV-2 infection: a single center experience (Cristina-Maria Sabo)